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Nepal is facing the serious problems of growing urbanization, dependency on food imports and constraining socio-economic structures. Urbanization leads to environmental degradation and pollution by the unsustainable practices of resource extraction. The country is extremely dependent on basic commodities including food, fuel for vehicles, cooking gas, and medicines from India, its main supplier. Also the high rate of food insecurity, poverty, frequent floods and weak local institutions is the problems that small landholdings face. As Nepal has poor and vulnerable populations the disasters and a climate change causes serious social, political, economic and institutional consequences .ISET-Nepal aimed to engage at the intersection of natural science, social science and local knowledge streams to overcome existing and emerging challenges for fine tuning existing policies and eventually forming new ones capable of adapting to new constraint as they rise.